Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Coughs
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
B2 bradykinin receptorP30411T23714
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00376Caspofungin--
BADD_D00377Caspofungin acetate--
BADD_D00378Cefaclor--
BADD_D00382Cefazolin--
BADD_D00388Cefixime0.003316%
BADD_D00395Cefpodoxime--
BADD_D00405Ceftriaxone0.316600%
BADD_D00407Cefuroxime0.002554%
BADD_D00408Cefuroxime axetil--
BADD_D00410Celecoxib--
BADD_D00412Cephalexin--
BADD_D00414Ceritinib--
BADD_D00415Cerivastatin--
BADD_D00417Cetirizine0.000861%
BADD_D00418Cetirizine hydrochloride--
BADD_D00419Cetrorelix--
BADD_D00422Cetuximab--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00429Chlorambucil0.000799%
BADD_D00434Chlorhexidine--
BADD_D00445Chlorpromazine--
BADD_D00451Cholestyramine0.002480%
BADD_D00455Choline fenofibrate--
BADD_D00457Choriogonadotropin alfa--
BADD_D00460Ciclesonide0.010208%
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00465Cilazapril monohydrate--
BADD_D00466Cilostazol--
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